Potential Side Effects of Commonly Prescribed Medications
IF YOU SUSPECT YOUR PET IS HAVING ADVERSE SIDE EFFECTS FROM THEIR MEDICATION, PLEASE LET US KNOW! WE HAVE ONLY LISTED THE MOST COMMON SIDE EFFECTS FROM PRESCRIBED DOSES HERE (NOT OVERDOSES). ANY MEDICATION HAS THE POTENTIAL TO CAUSE MORE SERIOUS EFFECTS INCLUDING ALLERGIC REACTIONS OR EVEN DEATH.
AntibioticsSide effects tend to be uncommon and mild. They usually involve GI upset (vomiting, diarrhea, poor appetite). Administering antibiotics with food can help.
Amoxicillin Clavamox Doxycyline Cephalexin Clindamycin Enrofloxacin
Pain Relievers/Anti-inflammatoriesNever give more than one NSAID at a time or an NSAID and a corticosteroid at the same time, this can cause bleeding GI ulcers.
Non-Steroidal Anti-Inflammatories NSAIDs:
Meloxicam (Meloxidyl, Ostilox, etc.) – GI distress most common (still rare), kidney toxicity is low, but cats should be given lower dose. Not FDA approved for chronic use in cats but is approved in virtually every other country.
Carprofen (Rimadyl) – GI distress most common (still rare), rarely can cause liver failure- monitor via bloodwork
Prednisone – increased thirst/urination, increased appetite, panting, behavioral changes
Prednisolone – same as prednisone
Temaril-P – same as prednisone, also drowsiness
Tramadol – drowsiness, well-tolerated
GastrointestinalBethanechol – vomiting, diarrhea, drooling, anorexia
Famotidine –GI side effects, headache, dry mouth
Lactulose – flatulence, distended stomach, cramping, diarrhea
Maropitant (Cerenia) –continued vomiting, drooling, diarrhea, anorexia
Metronidazole - Rarely neurologic toxicity (seizures, abnormal behavior)
Sucralfate – extremely safe
BehavioralCombinations of these drugs need to be carefully chosen by a doctor as some combinations can cause serotonin syndrome.
Acepromazine – hypotension, high heart rate, low heart rate, hypothermia, hyperthermia
Clomipramine – lethargy, anorexia, vomiting, diarrhea, increased liver enzymes, dry mouth, increased heart rate
Fluoxetine - lethargy, seizures, GI effects, anxiety, irritability, insomnia/hyperactivity, panting, aggressive behavior, anorexia (usually transient)
Trazadone – sedation, lethargy, ataxia, abnormal heart rhythm, increased anxiety, aggression